
01 / Dermatology
Retinaldehyde keeps retinoid results with less irritation
International Journal of Cosmetic Science · 2025
The discovery
Retinaldehyde converts to retinoic acid in one enzymatic step, so it works at lower irritation than retinol while still measurably improving fine lines and pigmentation.
In plain English
Your skin has to turn any vitamin A product into its active form before it can do anything. Retinaldehyde is already one step closer to that finish line than retinol, so skin needs to do less work — and you get the same smoothing and brightening with less redness and flaking.
Retinaldehyde reaches the same active form of vitamin A in one step — measurable smoothing with less irritation.
Why it matters
Most people quit retinoids because of stinging and peeling, not because they stop working. A better-tolerated form is the difference between a routine you abandon and one you keep for a year.
What this means for you
Start twice a week at night, buffer with moisturiser, and never layer it the same evening as an exfoliating acid.
The evidence
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In Evi: Overnight Retinal 0.1% Serum, Hyaluronic Acid 2% + B5





